20.03.2026; Миколаїв, Україна: VIII Міжнародна наукова конференція «Розвиток наук в умовах нової реальності: проблеми та перспективи»
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CURRENT TRENDS IN THE USE OF LIPOSOMAL DRUGS

  • Yuliia Malyshok,
  • Yevheniia Vasylenko
DOI: https://doi.org/10.62731/mcnd-20.03.2026.002
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Опубліковано 23.03.2026

Як цитувати

Malyshok, Y., & Vasylenko, Y. (2026). CURRENT TRENDS IN THE USE OF LIPOSOMAL DRUGS. Матеріали конференцій МЦНД, (20.03.2026; Миколаїв, Україна), 86–90. https://doi.org/10.62731/mcnd-20.03.2026.002

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Авторське право (c) 2026 Yuliia Malyshok, Yevheniia Vasylenko

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Анотація

Liposomes are promising nanoscale drug delivery systems due to their high biocompatibility and ability to encapsulate various therapeutic compounds. The article reviews current approaches to the development of liposomal drug formulations, including surface modification, the creation of stimulus-sensitive systems, and targeted delivery strategies. The advantages of liposomal preparations, their effect on increasing bioavailability and reducing the toxicity of drugs, as well as the prospects for their use in pharmacotherapy and personalised medicine are analysed.

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Посилання

  1. 1. Mehta, M., Polli, J. E., Seo, P., Bhoopathy, S., Berginc, K., Kristan, K., Cook, J., Dressman,
  2. J. B., Mandula, H., Munshi, U., Shanker, R., Volpe, D. A., Gordon, J., Veerasingham, S., Welink, J., Almeida, S., Gonzalez, P., Painter, D., Tsang, Y. C., Vaidyanathan, J., … Velagapudi, R. (2023). Drug Permeability - Best Practices for Biopharmaceutics Classification System (BCS)-Based Biowaivers: A workshop Summary Report. Journal of pharmaceutical sciences, 112(7), 1749–1762. https://doi.org/10.1016/j.xphs.2023.04.016
  3. 2. Samineni, R., Chimakurthy, J., & Konidala, S. (2022). Emerging Role of Biopharmaceutical Classification and Biopharmaceutical Drug Disposition System in Dosage form Development: A Systematic Review. Turkish journal of pharmaceutical sciences, 19(6), 706–713. https://doi.org/10.4274/tjps.galenos.2021.73554
  4. 3. Zhuang, J., Duan, Y., Zhang, Q., Gao, W., Li, S., Fang, R. H., & Zhang, L. (2020). Multimodal Enzyme Delivery and Therapy Enabled by Cell Membrane-Coated Metal-Organic Framework Nanoparticles. Nano letters, 20(5), 4051–4058. https://doi.org/10.1021/acs.nanolett.0c01654
  5. 4. Dahan, A., Miller, J. M., & Amidon, G. L. (2009). Prediction of solubility and permeability class membership: provisional BCS classification of the world's top oral drugs. The AAPS journal, 11(4), 740–746. https://doi.org/10.1208/s12248-009-9144-x
  6. 5. Zhang, Q., Fang, R. H., Gao, W., & Zhang, L. (2020). A Biomimetic Nanoparticle to "Lure and Kill" Phospholipase A2. Angewandte Chemie (International ed. in English), 59(26), 10461–10465. https://doi.org/10.1002/anie.202002782
  7. 6. Park, Y. I., Kwon, S. H., Lee, G., Motoyama, K., Kim, M. W., Lin, M., Niidome, T., Choi, J. H., & Lee, R. (2021). pH-sensitive multi-drug liposomes targeting folate receptor β for efficient treatment of non-small cell lung cancer. Journal of controlled release : official journal of the Controlled Release Society, 330, 1–14. https://doi.org/10.1016/j.jconrel.2020.12.011
  8. 7. Saadat, M., Mostafaei, F., Mahdinloo, S., Abdi, M., Zahednezhad, F., Zakeri-Milani, P., & Valizadeh, H. (2021). Drug delivery of pH-Sensitive nanoparticles into the liver cancer cells. Journal of Drug Delivery Science and Technology, 63, 102557. https://doi.org/10.1016/j.jddst.2021.102557
  9. 8. Liu, J., Huang, Y., Kumar, A., Tan, A., Jin, S., Mozhi, A., & Liang, X. J. (2014). pH-sensitive nano-systems for drug delivery in cancer therapy. Biotechnology advances, 32(4), 693–710. https://doi.org/10.1016/j.biotechadv.2013.11.009
  10. 9. Zhang, Y., Wang, Y., Lu, Y., Quan, H., Wang, Y., Song, S., & Guo, H. (2025). Advanced oral drug delivery systems for gastrointestinal targeted delivery: the design principles and foundations. Journal of nanobiotechnology, 23(1), 400. https://doi.org/10.1186/s12951-025-03479-8
  11. 10. Seynhaeve, A. L. B., Amin, M., Haemmerich, D., van Rhoon, G. C., & Ten Hagen, T. L. M. (2020). Hyperthermia and smart drug delivery systems for solid tumor therapy. Advanced drug delivery reviews, 163-164, 125–144. https://doi.org/10.1016/j.addr.2020.02.004
  12. 11. Aloss, K., & Hamar, P. (2023). Recent Preclinical and Clinical Progress in Liposomal Doxorubicin. Pharmaceutics, 15(3), 893. https://doi.org/10.3390/pharmaceutics15030893