THE MULTIDISCIPLINARY APPROACH TO THE STUDY OF AGING BIOMARKERS: FROM DERMATOGLYPHICS TO TISSUE MORPHOLOGY
Опубліковано 18.07.2025
Як цитувати
Завантаження
Авторське право (c) 2025 Maryna Yena

Ця робота ліцензується відповідно до Creative Commons Attribution-ShareAlike 4.0 International License.
Анотація
Aging is a complex, multifactorial process that affects all levels of biological organization — from molecular structures to entire organisms. Modern science increasingly demands the integration of diverse research methods, combining genetic, morphological, bioinformatic approaches with demographic and biometric observations [1]. In our study, we present an example of such a multidisciplinary strategy, combining results from dermatoglyphic analysis, tissue morphology research, and experimental studies of epigenetic aging.
Посилання
- 1. López-Otín C, Blasco MA, Partridge L, et al. The hallmarks of aging. Cell. 2013;153(6):1194-1217. DOI:10.1016/j.cell.2013.05.039.
- 2. Sharma, A., Sood V., Singh P., et al. Dermatoglyphics a review on fingerprints and their changing trends of use. Journal of Health and Research. 2018; 5(3): 167-172. DOI: 10.4103/cjhr.cjhr_112_17.
- 3. Coren S. Are fingerprints a genetic marker for handedness? Behavior Genetics. 1994; 24(2):141-8. DOI: 10.1007/BF01067817.
- 4. Arrieta M. C., Bistritz L., Meddings J. B. Alterations in intestinal permeability. Gut. 2006;55(10):1512-1520. DOI:10.1136/gut.2005.085373.
- 5. Katz J. A. Treatment of inflammatory bowel disease with corticosteroids. Gastroenterol Clin North Am. 2004; 33(2):171-89. DOI: 10.1016/j.gtc.2004.02.002.
- 6. Horvath S., Raj K. DNA methylation-based biomarkers and the epigenetic clock theory of ageing. Nat Rev Genet. 2018;19(6):371-384. DOI:10.1038/s41576-018-0004-3.
- 7. Meer M. V., Podolskiy D. I., Tyshkovskiy A., et al. A whole lifespan mouse multi-tissue DNA methylation clock. eLife. 2018;14:7:e40675. DOI:10.7554/eLife.40675.